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The analyses highlight the major limitations of current stethoscopes and the significant improvements the proposed system makes in challenging settings by minimizing both distortion of lung sounds and contamination by ambient noise.In this paper, we propose a novel method named Biomedical Confident Itemsets Explanation (BioCIE), aiming at post-hoc explanation of black-box machine learning models for biomedical text classification. Using sources of domain knowledge and a confident itemset mining method, BioCIE discretizes the decision sp