https://www.selleckchem.com/pr....oducts/GSK429286A.ht
From the magnitude of current change upon the addition of different concentrations of biotin solutions, the dissociation constant Kd is estimated to be 1.6 × 10-11 M. Since biotin is capable of conjugating with proteins, nucleotides and other bio-macromolecules without altering their properties, the present GFET sensor with its ultra-high sensitivity (0.37 pM) and specificity can be tailored to the rapid point-of-care detection of different types of desired biomolecules at very low concentration level through biotinylation as well as