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KLKs could be used as recurrence markers for prostate cancer. To investigate the differences in the characteristics and clinical outcomes of recently diagnosed patients with atrial fibrillation (AF) receiving different types of anticoagulants in a real-life setting. We retrospectively analyzed the charts of 1000 consecutive patients with non-valvular AF diagnosed at our institution or referred it to from 2013 to 2018. Over the observed period, the frequency of direct oral anticoagulation (DOAC) therapy use significantly increased (P =