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beneficial role of the clinical pharmacist in PIs associated with medical devices. There is a significant correlation between augmented renal clearance (ARC) and lower serum trough concentrations of vancomycin (VCM) during therapy. There is a need to evaluate the predictive performance of the population pharmacokinetic (PPK) model used for individual calculation of dosage regimens in ARC patients. Our study aimed to estimate the predictive performance differences of the reported VCM PPK software and in patients with varying renal funct