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However, after 12 and 16 weeks, the additional therapeutic effect of phototherapy weakened. NB-UVB phototherapy can provide a faster remission of severe AD in the first few weeks of dupilumab therapy. NB-UVB phototherapy can provide a faster remission of severe AD in the first few weeks of dupilumab therapy. Deep brain stimulation (DBS) is an approved treatment for movement disorders. Despite high precision in electrode placement, side effects do occur by current spread to adjacent fibers or nuclei. Directional leads (D-leads) are designed to adapt the volu