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96, 95%CI=0.8-4.9; p=0.14). Cutaneous SCC patients with S-ITM experienced outcomes similar to locally advanced non-metastatic cSCC patients. Larger studies are needed to guide incorporation into staging systems. Cutaneous SCC patients with S-ITM experienced outcomes similar to locally advanced non-metastatic cSCC patients. Larger studies are needed to guide incorporation into staging systems. The problem of lack of standardisation in target delineation and herewith the variability of target contours in Gamma Knife radiosurgery is as s