https://procollagencproteisign....als.com/index.php/mu
Using shorter LPS and LPS devoid of TLR2 activity, we further discovered this mTLR4-TRIF escape to be dependent on both the co-purifying lipoproteins as well as the full-length O antigen. Moreover, our data suggest that the O antigen could affect the binding for the leptospiral LPS into the co-receptor CD14 this is certainly essential for TLR4-TRIF activation. Overall, we explain right here a novel leptospiral immune escape procedure from
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