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The metabolite of tryptophan 6-formylindolo[3,2-b]carbazole (FICZ), an endogenous activator of AhR, plays bifunctional functions in cellular development and apoptosis. Nonetheless, whether and just how FICZ can reduce the poisoning of B[a]P together with method underlying this remain unclear. In this research, FICZ interfered using the poisoning of B[a]P in mouse hepatocarcinoma cell line Hepa1-6. The outcomes associated with the MTT assay indicated that FICZ and B[a]P made opposite impacts on cell prolif