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ADHD Treatment Medication Many people with ADHD can benefit from medication to improve their capacity for control and concentration. These medications are referred to as stimulants. They work by altering the brain chemical dopamine and norepinephrine. Atomoxetine and guanfacine as well as other non-stimulant medications help with ADHD. Treatment could consist of psychotherapy, medication or a combination of both. Behavioral therapy is most effective