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This study aimed to synthesize evidence of cancer patients' experiences of self-management of chemotherapy treatment-related symptoms. A systematic review of the literature was conducted to identify all qualitative or mixed studies published between January 2007 and December 2018, addressing the experiences of patients under 18 years submitted to chemotherapy treatments. A search in databases MEDLINE®, CINAHL®, and Psychology and Behavioural Sciences Collection was performed using specific key terms and Boolean operators. A thematic analysis was designed to