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51) as those without family history of diabetes. Fasting as well as postprandial triglyceride levels significantly correlated with HOMA-IR (r=0.35, P0.001 and r=0.39, P=0.04) only in those with a positive family history of diabetes but not in those without. Triglyceride levels mediated the associations of BMI (Δ β=-0.053) and waist circumference (Δ β=-0.075) with HOMA-IR. Triglyceride levels, both in the fasting and the postprandial state are associated with insulin resistance in NGT individuals with a family history of diabetes but