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A formulative study had been conducted, assessing the end result of medication attention to size circulation and dimensional stability of ethosomes by photon correlation spectroscopy. Ethosome morphology ended up being examined by cryogenic transmission electron microscopy, while the discussion between dimethyl fumarate and vesicles, therefore the medicine entrapment capacity had been respectively examined by FTIR and HPLC. To favor the topical application of ethosomes on mucosa and skin