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07, 7.26), depression (aHR = 4.94, 95% CI = 2.15, 11.8 and anxiety (aHR = 5.36, 95% CI = 2.98, 25.88), but no significant between-group differences were found for schizophrenia and other psychiatric disorders. In conclusion, the present nationwide population-based analysis revealed that Toxoplasma gondii infection in Taiwan significantly increases the risk for developing bipolar disorder, depression and anxiety, but not for schizophrenia and other psychiatric disorders.Toxoplasma gondii rhoptry protein TgROP18 is a polymorphic virulenc