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Synthesized NCu rendered a mixture of both metallic copper and cuprous oxide (Cu2O). HDPF viability reduces with publicity time and energy to the extracts (68-72% viability) and MGIC with 2-4 wt% NCu revealed antimicrobial activity contrary to the two tested strains.The aim of this research was to assess the actual properties of calcium-silicate based cements as retrograde filling out different pH and blood conditions utilizing micro-CT. Eighty-four teeth were obturated and after root-