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Although no significant differences were found between strains on the performance of these tasks, there was a significant difference in learning the association between lever pressing and food reward. Histological investigation confirmed the complete absence of commissural fibers from the corpus callosum, but also the hippocampal commissure, counter to a previous study. The results suggest spatial working memory and sustained attention are unaffected by the absence of these commissural fibers alone. The results suggest spatial working mem