https://www.selleckchem.com/GSK-3.html
There were about 1.93 million new cases and 940,000 deaths from colorectal cancer in 2020. The first-line chemotherapeutic drugs for colorectal cancer are mainly based on 5-fluorouracil (5-FU), but the use of these drugs is limited by the development of drug resistance. Consequently, there is a need for novel chemotherapeutic drugs for efficient treatment of colorectal cancer patients. In this study, we screened 160 FDA-approved drugs and identified that Cabazitaxel (CBT), a microtube inhibitor, can suppress colony formation and cell migration of