https://www.selleckchem.com/pr....oducts/4-phenylbutyr
Individually, the studies reported combinations of thermal and mechanical sensory impairments measured by QST. The meta-analysis showed significant sensory differences between patients and controls in warmth (effect size = 0.683; P less then .05) and cold detection thresholds (effect size = -0.580; P less then .001). Conclusion The results indicate that thermal sensitivity seems to be altered in patients with BMS compared to controls, suggesting a small-fibre neuropathy. However, study protocols were highly variable