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But, approximately 50% of hypertensive clients treated with lifestyle changes and antihypertensive drugs fail to attain hypertension control. Serum medication focus dimensions might be helpful to select the optimal drugs in modified doses also to determine nonadherence. Implementation of TDM in clinical program for antihypertensive drugs is dependent upon set up serum reference ranges. Widely used antihypertensive drugs were identified based on prescription information. The writers