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0 cm but not in with tumour size ≤ 4.0 cm (both P 0.05). Conclusions Tumour size of 4.0 cm is an independent predictor of poor prognosis and is associated with the surgical outcomes in PCS patients. Surgery significantly improves the prognosis in PCS patients with tumour size 4.0 cm. Our findings have the potential to assist clinicians to better evaluate the prognosis of PCS patients and develop optimal therapeutic strategies.Laser-accelerated proton bunches with kinetic energies up to several tens of MeV and at repetition