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This work underlines the great need for multidisciplinary platforms that integrates clinical research into paleopathology in order to successfully address the study of rare diseases from the past. Since OPK is only detected by X-rays, suspected cases of this bone lesion will only be identified when radiographs are taken for other purposes. Retrospective and large-scale studies of radiographs from other research in past populations. Retrospective and large-scale studies of radiographs from other research in past populations. Documented