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The clinical impact of stent strut thickness in coronary bifurcation lesions in small vessels has not been assessed in a real-world population. All 506 patients enrolled in the RAIN study, undergoing PCI in a vessel with a diameter 2.5 mm or less were retrospectively evaluated and divided into two groups according to stent strut thickness 74 μm (n = 206) versus 81 μm (n = 30; 87.1% of the lesions involved bifurcations. TLF [defined as a composite of myocardial infarction (MI) and target lesion revascularization (TLR)] was the primary