https://www.selleckchem.com/pr....oducts/Puromycin-2HC
Compared to WT, KO mice on HFD had hepatic enrichment of most cholesterol esters, monoglycerides, and certain sphingolipids species. Extended feeding with WD for 10 months led to extensive liver injury, fibrosis and hepatocellular carcinoma, with no difference between genotypes. Under alcohol exposure, KO and WT mice showed similar hepatic TG and liver enzyme levels. Interestingly, chow-fed KO showed significantly higher body and liver weight compared to WT, while KO mice on obesogenic diets had a shift towards larger lipid dropl
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