https://tenofovirinhibitor.com..../sars-cov-2-genomic-
Here, we characterize a disulfide-stabilized form of the peoples class I molecule HLA-A*0201 that is stable in the absence of peptide and that can readily exchange cognate peptides. We present X-ray crystal structures of the peptide-free state of HLA-A*0201, together with structures that have dipeptides bound into the A and F pouches. These structural snapshots reveal that the amino acid side stores lining the binding pockets switch in a coordinated manner between a peptide-free
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