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on of p-AMPK (p less then 0.001), in C2C12 muscle cells, showing increased signaling important for mitochondrial metabolism and biogenesis. Muscle lactate levels were also significantly increased following FO10 (p less then 0.05) and FO50 (p less then 0.001). In vivo, muscle protein expression of p-AMPK (p less then 0.05) and PGC-1α were increased, corroborating our in vitro results. Cytochrome C also significantly increased following FO200 intake. These results suggest that the effects of FO supplementation may manifest in a dose-respo