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Disease of neonates with WMHBV resulted in noticeable viremia for up to half a year. Conclusions Adult and neonate squirrel monkeys exhibited prolonged WMHBV viremia lasting 6-8 months. This will be higher than twice the period of viremia achieved various other nonhuman primates and suggests that squirrel monkeys is an appropriate model for testing HBV therapeutics. © 2020 The Authors. Hepatology Communications published by Wiley Periodicals, Inc., with respect to the United states Asso