https://www.selleckchem.com/pr....oducts/z-devd-fmk.ht
Glycan biosynthesis on cell surface proteins and lipids is orchestrated by different classes of enzymes and proteins including i. glycosyltransferases that add saccharides, ii. glycosidases that trim glycans, iii. Conserved Oligomeric Golgi complex (COG) members that regulate intracellular transport, iv. enzymes aiding the biosynthesis of sugar-nucleotides, and v. sulfotransferases. This manuscript describes a pooled 'glycoGene CRISPR' lentiviral library that targets 347 human genes involved in the above processes. Approximately 10 s