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© The author(s).Bladder disease (BC) is one of the most prevalent cancers global and has high rates of relapse and progression. Cell unit pattern associated 5 (CDCA5), a substrate regarding the anaphase-promoting complex, was reported is upregulated in a number of types of cancer; nonetheless, the function of CDCA5 in BC continues to be uncertain. In this study, we observed that BC areas had greater quantities of CDCA5 appearance than adjacent normal areas. We also found that high