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This article explores the current status of generally understudied patient groups in NSCLC and proposes future directions in therapeutic strategies. mutations reported in non-small cell lung cancer (NSCLC) represent a significant percentage of patients diagnosed with NSCLC. However, there still remains no therapeutic option designed to target KRAS. In an era with immunotherapy as a dominant treatment option in metastatic NSCLC, the role of immunotherapy in. mutated patients is not clear. Eligible patients diagnosed with NSCLC and foun