https://www.selleckchem.com/pr....oducts/gilteritinib-
Ribonucleotideprotein interactions play crucial roles in a number of biological processes. Unlike the RNAprotein interface where van der Waals contacts are prevalent, the recognition of a single ribonucleotide such as ATP by a protein occurs predominantly through hydrogen-bonding interactions. As a first step toward understanding the role of hydrogen bonding in ribonucleotideprotein recognition, the present work employs density functional theory to provide a detailed quantum-mechanical analysis of the structural and energet