https://www.selleckchem.com/pr....oducts/tolebrutinib-
The copper-catalyzed azide-alkyne cycloaddition (CuAAC) click reaction is among the most extensively used strategies for the post-polymerization modification of COFs. This work shows a new procedure for the postsynthetic functionalization of imine-based COFs by using a heterogeneous solid-gas reaction between alkyne-functionalized COFs and azides in the absence of a copper catalyst. This new alternative represents a step forward towards a greener postsynthetic modification of COFs opening a high potential for the developm