https://www.selleckchem.com/products/kpt-8602.html
Histopathological assessments were performed on days 14, 21, and 28. MEL treatment resulted in decreased motor dysfunction, mechanical and cold allodynia, auricle temperature, and also ameliorated weight loss. Moreover, MEL suppressed MMP-9 activity while increasing that of MMP-2 post-SCI indicating its anti-neuroinflammatory effects. Also, MEL significantly preserved white matter myelinated areas and the number of sensory neurons post-SCI. The results suggest MEL as a promising candidate for medical therapies with advantageous effects
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