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Platelet count at presentation was higher in recurrences than in the first disease episode (P = .016) and ADAMTS13 activity less then 5% was more frequent in the last group (P = .016). There was no significant difference in the rate of refractoriness or exacerbations. In conclusion, first aTTP episodes had a higher probability of short-term mortality compared to relapsed aTTP episodes according to the MITS and French TMA Reference Center Score. Erythrocytosis is a condition with an excessive number of erythrocytes, accompanied by an elev