https://www.selleckchem.com/pr....oducts/srt2104-gsk22
Corticosteroid (CS) therapy for infectious and rheumatological diseases showed to decrease serum magnesium (Mg ) level and induce muscle atrophy in patients. The present study investigated the effects of Mg supplementation on preventing CS-induced muscle atrophy in an animal model, which provided experimental data for potential clinical translation. Twelve 24-week-old male Sprague-Dawley rats were treated with lipopolysaccharide (LPS) and CS methylprednisolone (MPS) to induce muscle atrophy, with half of the rats also given d
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