https://www.selleckchem.com/pr....oducts/wnt-agonist-1
The paired measurement of RNA and surface proteins in single cells with cellular indexing of transcriptomes and epitopes by sequencing (CITE-seq) is a promising approach to connect transcriptional variation with cell phenotypes and functions. However, combining these paired views into a unified representation of cell state is made challenging by the unique technical characteristics of each measurement. Here we present Total Variational Inference (totalVI; https//scvi-tools.org ), a framework for end-to-end joint analysis of CITE-s