https://abemaciclibinhibitor.c....om/using-osteopathic
Optogenetic perturbations, live imaging, and time-resolved ChIP-seq assays in Drosophila embryos were utilized to dissect the ERK-dependent control over the HMG-box repressor Capicua (Cic), which plays critical roles in development and it is deregulated in person spinocerebellar ataxia and cancers. We established that Cic target genetics are triggered before significant downregulation of atomic localization of Cic and demonstrated that their activation is preceded by quick diss