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We created REPAC, a framework for the analysis of APA from RNA-sequencing data. Making use of REPAC, we investigate the landscape of APA due to activation of B cells. We additionally reveal that REPAC is quicker than alternate practices by at the least 7-fold and therefore it scales really to a huge selection of examples. Overall, the REPAC strategy provides an exact, easy, and convenient solution when it comes to research of APA. Assessing gender variations in publication pri