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ADHD Stimulant Medication Stimulants can help with symptoms such as inattention and hyperactivity, with effects typically felt within 30 to 60 minutes. They are the first line treatment for people suffering from ADHD. Stimulants alter the neurotransmitters that are key to their function, dopamine and noradrenaline that are found in the tiny gaps between neurons, also known as synapses. They also help connected neurons communicate with