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9 (5.9) and 5.1 (6.3) years respectively. People with psoriasis had a higher incidence rate of serious infection (20.5/1000 person-years, 95% CI 20.0-21.0, n=7629) compared with those without psoriasis (16.1/1000 person-years, 95% CI 15.9-16.3, n=30756). The fully adjusted hazard ratio for the association between psoriasis and serious infection was 1.36 (95%CI 1.31-1.4, with results similar across the other outcomes. CONCLUSIONS Psoriasis is associated with a small increase in the risk of serious infection. Further research is needed to