https://www.selleckchem.com/pr....oducts/spautin-1.htm
Over time, we observed an increase in patient exposure to thiopurine (p=0.0025), cyclosporin (p=0.0002) and anti-tumour necrosis factor (p0.00001) coupled with a shift to laparoscopic technique (p0.00001), stapled IPAA (p0.00001), J pouch configuration (p0.00001), a modified two-stage procedure (p=0.00012) and a decline in defunctioning ileostomy rate at time of IPAA (p=0.00002). Apart from pouchitis, there was no significant difference in surgical and chronic inflammatory pouch outcomes with time. Despite greater pati
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