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In conclusion, we generated and characterized iPSCs derived from cystic and healthy control renal epithelial cells, that could be useful for in vitro modeling of renal development overall and cystogenesis in particular. © 2020 The Authors. STEM CELLS TRANSLATIONAL MEDICATION published by Wiley Periodicals, Inc. on behalf of AlphaMed Press.BACKGROUND physical exercise (PA) is a recognized contributor to healthy ageing. But, nearly all researches exploring its o