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05). Among the four quadrants, only the inferior nasal (IN) quadrant showed no difference in microvascular density between mild and moderate groups. Ridge regression indicated that microvascular density values in all three layers were more strongly correlated with axial length (AL) (scaled estimates -0.139, -0.103, -0.154; all p 0.001) than with spherical equivalent (SE) (scaled estimates -0.052, -0.096, -0.057; all p 0.05). We characterized a stepwise and quadrant alteration of retinal microvascular density from mild to extreme