https://www.selleckchem.com/pr....oducts/rgd-peptide-g
FUZ was found to promote energy metabolism through the phosphoinositide 3-kinase (PI3K)/protein kinase B (AKT) pathway, and overexpression of FUZ increased both lactic acid and 18F-FDG uptake. Moreover, FUZ knockdown significantly inhibited the migration and invasion of NSCLC cells. In vivo, FUZ knockdown can significantly inhibit tumor proliferation in the xenograft model, which was well identified by Micro-PET scan. Conclusion The present finding in vitro and vivo show that FUZ is involved in NSCLC cell energy metabolism,
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