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Overproduction regarding the gaseous mediator hydrogen sulfide (H2S) is implicated when you look at the pathogenesis of neurological and metabolic deficits connected with Down syndrome. Several outlines of information suggest that an important chemical in charge of H2S overproduction in Down problem is cystathionine-β-synthase (CBS), an enzyme localized on chromosome 21. The present research explored the chance that a second H2S-producing chemical, 3-mercaptopyruvate sulfurtransferase (3-MST),
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