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3-350 μM for determination of adrenalone and folic acid, respectively. The NiO/SWCNTs/1B3MIMS/CPE was then used as an ultrasensitive electroanalytical sensor for determination of adrenalone and folic acid in injection samples with recovery ratio between 98.2-103.66 %.Frequency of seizures is often managed by a wide group of antiepileptic drugs. Regarding the pharmacokinetic variability, narrow targeted range, and difficulty of detecting signs of toxicity based on laboratory responses, therapeutic monitoring of antiepileptic drugs can pla