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047) and associated with the duration of disorder and lifetime occurrence of substance use disorder (p = 0.018). FA decrease was found in the corpus callosum of BPI patients (p 0.01). MDD patients showed FA decrease in the right cerebellar middle peduncle (RCMP) (p 0.01). In BPI patients, the duration of disorder associated with FA increase in RCMP (p 0.05). No FA decrease was detected in patients with WMHs as compared with those without. Preceding illness burden associated modestly with WMHs, and FA increase in RCMP in
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