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Relapsing polychondritis (RPC) is a rare autoimmune disease and its early diagnosis remains challenging. Defining the clinical patterns and disease course may help early recognition of RPC. Sixty-six males and 60 females were included in this study. The average age at onset were 47.1 ± 13.8years and the median follow-up period was 18months. Correlation analysis revealed a strong negative correlation between airway involvement and auricular chondritis (r = - 0.75, P 0.001). Four distinct clinical patterns were identified Ear pattern