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001). Post-regionalization patients experienced fewer total (26.2% from 38.6%, p less then 0.001) and major (9.6% from 13.6%, p=0.01) complications. The association between regionalization and decreased length of stay and morbidity was independent of surgical approach and case volume in mixed multivariate models. CONCLUSIONS After the successful implementation of thoracic surgery regionalization in our American healthcare network, pulmonary resection volume increased, and practice shifted to majority VATS and minimum ICU utilization. Regi