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Also, it had been uncovered that OsCERK1 decreases the tolerance to CuO NPs stress by managing the anti-oxidant system and increasing the accumulation of H2O2 in rice. In inclusion, CuO NPs treatment significantly enhances the basal resistance against M. oryzae that will be mediated by OsCERK1. To conclude, this research demonstrated a dual role of OsCERK1 in response to CuO NPs tension and M. oryzae infection by modulating ROS buildup, which expands our comprehension in regards to the crossta