https://www.selleckchem.com/products/ON-01910.html
indicate that IATL may provide a future potential therapy for pancreatic cancer. The phosphodiesterase inhibitor sildenafil is a promising treatment for neurodegenerative disease, but it can cause oxidative stress in photoreceptors ex vivo and degrade visual performance in humans. Here, we test the hypotheses that in wildtype mice sildenafil causes i) wide-spread photoreceptor oxidative stress in vivo that is linked with ii) impaired vision. In dark or light-adapted C57BL/6 mice ± sildenafil treatment, the presence of oxidative stress
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