https://www.selleckchem.com/pr....oducts/pf-477736.htm
This MGIA may be valuable as a surrogate marker of host immunity in a personalized medicine approach.The ability to genetically engineer pathogenic mycobacteria has increased significantly over the last decades due to the generation of new molecular tools. Recently, the application of the Streptococcus pyogenes and the Streptococcus thermophilus CRISPR-Cas9 systems in mycobacteria has enabled gene editing and efficient CRISPR interference-mediated transcriptional regulation. Here, we converted CRISPR interference into an efficient gen